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Stat3 Antibody
产品编号: ICP6015
  • 100.00µg
    ¥2950.00
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详细介绍

Stat3 Antibody

Catalog#

Product Description

ICP6015

Stat3 antibody was developed using a short peptide based on human stat3 sequence. The antibodies were tested against human cell and mouse tissues extract (spleen) to detect Stat3 in western blot.  Immunohistochemistry was tested using human breast cancer tissue.

Western blot analysis of the extract from mouse spleen and human lump using ICP6015 with (A) and without (B) competitive antigen peptide.
Species
Rabbit
Formulation
250 µg/mL in PBS, pH7 with  50% glycerol
Immunogen
Human Stat3 peptide (720-732aa) KLH conjugates
Purification
Affinity purified chromatography
Specificity
The antibody recognizes Stat3 from human and mouse.
Applications
ELISA (1:2500); WB (1:2500); IHC (1:100)
Scientific Description
STAT1 and STAT2 were the first two STAT (signal transducers and activators of transcription) proteins discovered.  They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction.  Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6.[1] Specific functions of the STAT proteins are poorly understood.  They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

Product Specific References

1. Cell, 1996. 84(3): 331-334. doi:10.1016/S0092-8674(00)81277-5

2. Eur. J. Biochem. 1997. 248(3): 615-633, doi:10.1111/j.1432-1033.1997.00615.x



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