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Stat1 Antibody
产品编号: ICP6010
  • 100.00µg
    ¥2950.00
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详细介绍

Stat1 Antibody

Catalog#

Product Description

ICP6010

The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ. These antibodies were raised based on the human Stat1 sequence (690-720 aa) and tested in western blotting of human and mouse cell lysate and mouse tissue (spleen) extract to detect Stat1.

Western blot analysis of the extract from mouse spleen ICP0610.
  1. A: Spleen from control             mouse
  2. B: Spleen from mouse             treated with LPS
Species
Rabbit
Formulation
250 µg/mL in PBS, pH7 with  50% glycerol
Immunogen
Human Stat1 peptide KLH conjugates
Purification
Affinity purified chromatography
Specificity
The antibody recognizes Stat1 from human and mouse.
Applications
ELISA; WB; IHC
Scientific Description
STAT1 and STAT2 were the first two STAT (signal transducers and activators of transcription) proteins discovered.  They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction.  Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6.[1] Specific functions of the STAT proteins are poorly understood.  They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

Product Specific References

1. Cell, 1996. 84(3): 331-334. doi:10.1016/S0092-8674(00)81277-5

2. Eur. J. Biochem. 1997. 248(3): 615-633, doi:10.1111/j.1432-1033.1997.00615.x

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