Thyroxine (T4) Antibody

Catalog#

Product Description

ICP1325

This antibody was developed using Tthyroxine (T4) linked to the immunogenic carrier protein -KLH conjugates as the immunogen, The T4-specific antibodies was and affinity purified with antigen-specific affinity chromatography and eluted by competitive free T4. The antibody could be utilized for detection, quantization and affinity isolation and purification of estradiol in biofluid.

Competitive ELISA

Structure of the T4 Immunogen

Species

Rabbit

Formulation

250 µg/mL in PBS with 50% glycerol

Immunogen

T4-linked KLH protein conjugates

Purification

Antigen-specific immune-affinity chromatography and free T4 competitive elution

Specificity

The antibody recognizes free estradiol.

Applications

Quantitative ELISA: IC50=0.8 ng/mL, Immunoaffinity Chromatography

Scientific Description

Thyroxine, also called 3,5,3′,5′-tetraiodothyronine, or T₄, one of the two major hormones secreted by thethyroid gland (the other is triiodothyronine). Thyroxine’s principal function is to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Thyroxine is formed by the molecular addition of iodine to the amino acid tyrosine while the latter is bound to the protein thyroglobulin. Excessive secretion of thyroxine in the body is known as hyperthyroidism, and the deficient secretion of it is called hypothyroidism

Storage & Stability

Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored.

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Thyroxine (T4) Antibody

Catalog# Product Description	ICP1325 This antibody was developed using Tthyroxine (T4) linked to the immunogenic carrier protein -KLH conjugates as the immunogen, The T4-specific antibodies was and affinity purified with antigen-specific affinity chromatography and eluted by competitive free T4. The antibody could be utilized for detection, quantization and affinity isolation and purification of estradiol in biofluid.	Competitive ELISA Structure of the T4 Immunogen
Species	Rabbit
Formulation	250 µg/mL in PBS with 50% glycerol
Immunogen	T4-linked KLH protein conjugates
Purification	Antigen-specific immune-affinity chromatography and free T4 competitive elution
Specificity	The antibody recognizes free estradiol.
Applications	Quantitative ELISA: IC50=0.8 ng/mL, Immunoaffinity Chromatography
Scientific Description	Thyroxine, also called 3,5,3′,5′-tetraiodothyronine, or T₄, one of the two major hormones secreted by thethyroid gland (the other is triiodothyronine). Thyroxine’s principal function is to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Thyroxine is formed by the molecular addition of iodine to the amino acid tyrosine while the latter is bound to the protein thyroglobulin. Excessive secretion of thyroxine in the body is known as hyperthyroidism, and the deficient secretion of it is called hypothyroidism
Storage & Stability	Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored.